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Xin-Fu Zhou Selected Research

Brain-Derived Neurotrophic Factor (BDNF)

1/2022The role of brain-derived neurotrophic factor and the neurotrophin receptor p75NTR in age-related brain atrophy and the transition to Alzheimer's disease.
1/2022proBDNF/p75NTR promotes rheumatoid arthritis and inflammatory response by activating proinflammatory cytokines.
8/2021Brain-derived neurotrophic factor and its related enzymes and receptors play important roles after hypoxic-ischemic brain damage.
1/2021Analysis of blood mature BDNF and proBDNF in mood disorders with specific ELISA assays.
1/2020Pro-BDNF Knockout Causes Abnormal Motor Behaviours and Early Death in Mice.
10/2019Panax notoginsenoside Rb1 Restores the Neurotrophic Imbalance Following Photothrombotic Stroke in Rats.
7/2019The Level of proBDNF in Blood Lymphocytes Is Correlated with that in the Brain of Rats with Photothrombotic Ischemic Stroke.
1/2019The effects of rotenone on TH, BDNF and BDNF-related proteins in the brain and periphery: Relevance to early Parkinson's disease.
3/2018Investigation of Mature BDNF and proBDNF Signaling in a Rat Photothrombotic Ischemic Model.
1/2018ProBDNF/p75NTR/sortilin pathway is activated in peripheral blood of patients with alcohol dependence.
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Xin-Fu Zhou Research Topics

Disease

37Alzheimer Disease (Alzheimer's Disease)
11/2023 - 10/2006
14Neuroinflammatory Diseases
01/2022 - 10/2009
9Amyloid Plaque
11/2023 - 03/2009
9Pain (Aches)
01/2022 - 05/2002
8Ischemia
08/2022 - 04/2017
8Ischemic Stroke
08/2022 - 04/2015
7Parkinson Disease (Parkinson's Disease)
10/2022 - 12/2015
7Neoplasms (Cancer)
11/2017 - 02/2013
6Spinal Cord Injuries (Spinal Cord Injury)
10/2022 - 01/2005
6Inflammation (Inflammations)
07/2021 - 12/2005
5Cognitive Dysfunction
01/2022 - 03/2009
5Hypoxia (Hypoxemia)
08/2021 - 04/2015
5Huntington Disease (Huntington's Disease)
01/2020 - 01/2009
5Stroke (Strokes)
10/2019 - 08/2016
4Brain Ischemia (Cerebral Ischemia)
10/2019 - 04/2017
4Hyperalgesia
01/2014 - 06/2003
3Neurodegenerative Diseases (Neurodegenerative Disease)
12/2021 - 11/2017
3Brain Injuries (Brain Injury)
06/2021 - 01/2019
3Gliosis
04/2018 - 10/2009
3Bone Fractures (Bone Fracture)
03/2018 - 07/2006
3Traumatic Brain Injuries (Traumatic Brain Injury)
01/2018 - 07/2014
3Glioma (Gliomas)
07/2015 - 08/2013
3Neuralgia (Stump Neuralgia)
06/2006 - 05/2002
2Cerebral Infarction
08/2022 - 10/2019
2Hypertrophy
04/2022 - 01/2014
2Atrophy
01/2022 - 11/2014
2Body Weight (Weight, Body)
01/2022 - 01/2014
2Mood Disorders (Mood Disorder)
01/2021 - 11/2016
2Salter-Harris Fractures
11/2018 - 07/2006
2Neuroblastoma
10/2018 - 01/2018
2Alcoholism (Alcohol Abuse)
01/2018 - 01/2017
2Pancreatitis
01/2018 - 08/2016
2Genomic Instability
01/2016 - 02/2009
2Hypersensitivity (Allergy)
01/2016 - 09/2011
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
10/2022
1Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
08/2022
1Chronic Disease (Chronic Diseases)
04/2022
1Diabetic Cardiomyopathies
04/2022
1Depressive Disorder (Melancholia)
01/2022
1Insulin Resistance
01/2022
1Obesity
01/2022
1Rheumatoid Arthritis
01/2022
1Motor Neuron Disease (Primary Lateral Sclerosis)
12/2021
1Frontotemporal Dementia (Semantic Dementia)
12/2021
1Nervous System Diseases (Neurological Disorders)
11/2021

Drug/Important Bio-Agent (IBA)

25Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2022 - 01/2005
21Proteins (Proteins, Gene)FDA Link
01/2022 - 06/2006
18Amyloid beta-PeptidesIBA
12/2021 - 10/2006
13Amyloid (Amyloid Fibrils)IBA
11/2023 - 02/2009
9Nerve Growth Factors (Neurotrophins)IBA
10/2022 - 06/2003
9sortilinIBA
10/2019 - 06/2013
7EdaravoneIBA
08/2022 - 04/2015
6AntibodiesIBA
01/2021 - 03/2002
6Nerve Growth Factor Receptor (Nerve Growth Factor Receptor, Low Affinity)IBA
07/2019 - 02/2013
6Nerve Growth Factor (NGF)IBA
01/2018 - 03/2002
5LipopolysaccharidesIBA
01/2022 - 10/2019
4Nerve Growth Factor Receptors (Neurotrophin Receptors)IBA
01/2022 - 01/2016
4CytokinesIBA
01/2022 - 04/2018
4Free Radical ScavengersIBA
12/2021 - 04/2015
4EnzymesIBA
01/2021 - 10/2015
4brain-derived neurotrophic factor precursorIBA
01/2021 - 11/2006
3Peptides (Polypeptides)IBA
11/2023 - 10/2012
3CurcuminIBA
01/2022 - 02/2009
3Neuroprotective AgentsIBA
04/2021 - 01/2017
3scutellarinIBA
01/2021 - 04/2018
3Therapeutic UsesIBA
01/2021 - 03/2008
3Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA
01/2018 - 08/2016
3nafamostatIBA
01/2018 - 08/2016
2Caspase 3 (Caspase-3)IBA
08/2022 - 01/2018
2Streptozocin (Streptozotocin)FDA Link
01/2022 - 08/2021
2Biomarkers (Surrogate Marker)IBA
01/2022 - 07/2019
2Messenger RNA (mRNA)IBA
01/2022 - 07/2019
2Glucose (Dextrose)FDA LinkGeneric
01/2022 - 01/2019
2Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA
07/2021 - 12/2015
2Recombinant ProteinsIBA
03/2021 - 01/2020
2Panax notoginsenoside saponin Rb1IBA
10/2019 - 01/2018
2Nimodipine (Modus)FDA LinkGeneric
10/2019 - 04/2017
2ginsenoside Rb1IBA
10/2019 - 04/2017
2RotenoneIBA
01/2019 - 12/2015
2CopperIBA
10/2018 - 01/2018
2MetalsIBA
10/2018 - 01/2018
2Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
01/2016 - 09/2011
2Morphine (MS Contin)FDA LinkGeneric
01/2014 - 01/2010
2Neutralizing AntibodiesIBA
11/2010 - 06/2003
2Grape Seed ExtractIBA
02/2009 - 01/2009
2PolyphenolsIBA
02/2009 - 01/2009
1Vesicle-Associated Membrane Protein 2 (VAMP2)IBA
08/2022
1Free RadicalsIBA
04/2022
1CollagenIBA
04/2022
1Reactive Oxygen Species (Oxygen Radicals)IBA
04/2022
1DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
04/2022
1Hormones (Hormone)IBA
01/2022
1Hydrocortisone (Cortisol)FDA LinkGeneric
01/2022
1hyperosideIBA
12/2021

Therapy/Procedure

7Therapeutics
11/2023 - 01/2010
3Transplantation
11/2021 - 07/2014
3Axotomy
06/2006 - 05/2002
2Oral Administration
12/2021 - 04/2015
2Cell- and Tissue-Based Therapy (Cell Therapy)
11/2021 - 01/2018
2Immunotherapy
01/2010 - 03/2009